Tokyo, Japan - (Novemba 15, 2022) - UDaiichi Sankyo (TSE: 4568) namuhla umemezele ukuthi esivivinyweni sokuhlolwa ukusebenza nokuphepha kokugoma i-booster nge-DS-5670, umuthi wokugomela i-mRNA ngokumelene nesifo esithathelwanayo se-coronavirus (COVID -19) ithuthukiswa ngu-Daiichi Sankyo (ngemuva kwalokhu, ukuhlolwa kokugoma kwe-booster), isiphetho esiyinhloko safinyelelwa.Uhlolo lokugomela i-booster luhlanganisa cishe abantu abadala abanempilo e-Japan abangu-5,000 kanye nezifundo esezikhulile ababeqede uchungechunge oluyinhloko (imithamo emibili) yemithi yokugoma ye-mRNA egunyazwe e-Japan okungenani izinyanga eziyisithupha ngaphambi kokubhaliswa.NgoJanuwari 2022, ukuhlolwa kwaqalwa njengesivivinyo sesigaba 1/2/3 ukuze kuhlolwe ukusebenza nokuphepha kokugoma i-booster nge-DS-5670 kusetshenziswa imigomo ye-mRNA egunyazwe e-Japan njengokulawula.I-GMFR yokunciphisa i-antibody titer ngokumelene ne-SARS-CoV-2 (uhlobo lwangempela) egazini emasontweni amane ngemuva kokugonywa kwe-booster, isiphetho sokuqala sohlolo lokugomela i-booster, ibonise idatha ephezulu kanye nokungabi ngaphansi kwe-DS-5670 emithini yokugoma ye-mRNA ( original strain) okugunyazwe e-Japan, kufezwe inhloso ehlosiwe.Akukho ukukhathazeka ngokuphepha okuhlonziwe.Imiphumela enemininingwane yocwaningo lokugoma i-booster izokwethulwa ezingqungqutheleni zezemfundo nasemaphepheni ocwaningo.Ngokusekelwe emiphumeleni yocwaningo, u-Daiichi Sankyo uzoqhubeka nokulungiselela isicelo esisha somuthi wokugomela i-mRNA ngoJanuwari 2023. Ngaphezu kwalokho, u-Daiichi Sankyo uhlela ukwenza izivivinyo zomtholampilo zokugomela i-bivalent yohlobo lokuqala kanye nezinhlobo ze-Omicron ngokumelene nama-coronavirus amasha, eziqhubeka zishintshashintsha.U-Daiichi Sankyo uzozama ukuqinisa uhlelo lokuthuthukiswa komgomo kanye nokukhiqizwa komgomo we-mRNA ukuze kuqinisekiswe ukutholakala okuzinzile ngezikhathi ezejwayelekile kanye nokuhlinzekwa ngokushesha kwemithi yokugoma uma kwenzeka kuqubuka izifo ezithathelwanayo ezivelayo neziphinde ziqhamuke.
Mayelana ne-DS-5670 DS-5670 umuthi wokugomela i-mRNA ngokumelene ne-COVID-19 usebenzisa ubuchwepheshe bokulethwa kwe-nucleic acid inoveli etholwe ngu-Daiichi Sankyo, oklanyelwe ukukhiqiza amasosha omzimba ngokumelene nesizinda sokubopha i-receptor (RBD) ye-spike protein yenoveli coronavirus, futhi ngaleyo ndlela. kulindeleke ukuthi ibe nokuvinjelwa okufiselekayo ngokumelene nokuphepha kwe-COVID-19 no-2.Ngaphezu kwalokho, i-Daiichi Sankyo ihlose ukugoma i-mRNA engasatshalaliswa ebangeni lokushisa eliqandisiwe (2-8°C)
Isikhathi sokuthumela: Dec-17-2022
