I-Amoxicillin Trihydrate (61336-70-7)
Incazelo
● I-Amoxicillin Trihydrate (61336-70-7)
● Inombolo ye-CAS: 61336-70-7
● I-EINECS No.:248-003-8
● MF: C16H19N3O5S
● Iphakheji: 25kg / isigubhu
Imininingwane Yomkhiqizo
I-Amoxicillin trihydrate, i-semi-synthetic broad-spectrum penicillin, ine-spectrum ye-antibacterial efanayo, umphumela kanye nokusetshenziswa njenge-ampicillin.I-Amoxicillin trihydrate iyi-hydrate ewuhlobo lwe-trihydrate ye-amoxicillin;isibulala-magciwane se-semisynthetic, esisetshenziswa sona sodwa noma sihlanganiswe ne-potassium clavulanate (ngaphansi kwegama lokuhweba i-Augmentin) ekwelapheni izifo ezihlukahlukene ezibangelwa amagciwane.Inendima njengesidakamizwa esilwa namagciwane kanye ne-ejenti ye-antimicrobial.Iqukethe i-amoxicillin.I-Amoxicillin iyi-anti-spectrum ebanzi, i-semisynthetic ye-aminopenicillin esebenzayo enomsebenzi we-bactericidal.I-Amoxicillin ibophezela futhi ingasebenzi iprotheni ebopha i-penicillin (PBP) 1A etholakala kulwelwesi lwangaphakathi lodonga lwamaseli ebhaktheriya.Ukungasebenzi kwama-PBP kuphazamisa ukuxhumana okuphambanayo kwamaketango e-peptidoglycan adingekayo ukuze kuqine udonga lwamaseli ebhaktheriya kanye nokuqina.Lokhu kuphazamisa ukwakheka kodonga lwamangqamuzana ebhaktheriya futhi kubangele ukuthi udonga lwamangqamuzana ebhaktheriya lube buthaka futhi lubangele i-cell lysis.
I-Amoxicillin yatholwa ngo-1958 futhi yaqala ukusetshenziswa kwezokwelapha ngo-1972. I-Amoxil yagunyazwa ukusetshenziswa kwezokwelapha e-United States ngo-1974, nase-United Kingdom ngo-1977. Isohlwini lwe (WHO) lweWorld Health Organization's List of Essential Medicines.It. ingenye yemithi elwa namagciwane esetshenziswa kakhulu ezinganeni.I-Amoxicillin itholakala njengomuthi ojwayelekile. Ngo-2020, kwaba umuthi wama-40 ovame ukunikezwa e-United States, onemiyalelo engaphezu kwezigidi eziyi-15.
Isicelo
Isetshenziselwa ukwelapha izifo ezibangelwa amagciwane, njengezifo zesifuba (okuhlanganisa inyumoniya) namathumba amazinyo.Ingasetshenziswa kanye namanye ama-antibiotics kanye nemithi yokwelapha izilonda zesisu.Ngokuvamile kunqunyelwe izingane, ukwelapha izifo ezindlebeni kanye nezifo zesifuba.
| Imigomo yokuhlola | Amazinga | Imiphumela |
| Isivivinyo | 95.0%~102.0% | 99.9% |
| PH | 3.5~5.5 | 4.6 |
| Ukubukeka kwesixazululo | 0.5mol/L HCL≤2# 2mol/L NH4 OH≤2# | 1#1# |
| Amanzi | 11.5%~14.5% | 13.2% |
| Izinto ezihlobene | Ukungcola (ubuningi.)≤1.0% | 0.13% |
| Ukujikeleza kwe-optical okuqondile | +290''~+315'' | +305° |
| Umlotha one-sulfate | ≤1.0% | 0.1% |
| I-NN-Dimethylannline | ≤20ppm | Ayikaze isetshenziswe ekukhiqizeni |
| I-Methylen chloride | ≤600ppm | 296 ppm |
| I-Triethylamine | ≤320ppm | 155ppm |
| I-acetone | ≤3000ppm | awu 95ppm |
| Isiphetho: Ihambisana ne-EP 6th Standard. | ||
