I-Ciprofloxacin Base(86483-48-9)
Incazelo Yomkhiqizo
● Isisekelo se-Ciprofloxacin siyi-fluoroquinolone ene-spectrum ye-antibacterial efanayo ne-norfloxacin, futhi umsebenzi wayo wokulwa namagciwane unamandla phakathi kwe-fluoroquinolones esetshenziswa kakhulu.Ngaphezu komsebenzi wayo ophezulu we-antibacterial ngokumelene ne-bacilli ye-gram-negative, futhi inomphumela omuhle we-antibacterial ku-Staphylococcus spp.futhi ayisebenzi kahle kune-Staphylococcus spp.ngokumelene ne-pneumococcus kanye ne-streptococcus spp.
● Isisekelo se-Ciprofloxacin sisetshenziselwa ukwelapha izifo zemigudu yokuphefumula, izifo zomgudu womchamo, izifo zamathumbu, izifo zazo zonke izinhlelo ze-biliary tract, intra-abdominal infections, izifo zezifo zabesifazane, izifo zamathambo namalunga kanye nezifo ezimbi kakhulu. umzimba.
| Izivivinyo | Imibandela Yokwamukela | Imiphumela | |
| Izinhlamvu | Cishe i-crystalline powder emhlophe noma ephuzi | Impushana ecwebezelayo ephuzi | |
| Ukuhlonza | I-IR : Ihambisana ne-spectrum ye-Ciprofloxacin RS. | Kuyavumelana | |
| I-HPLC:Isikhathi sokugcina sesiqongo esikhulu sesixazululo Sesampuli sihambisana naleso Sesixazululo Esijwayelekile , njengoba sitholwe ku-Assay. | |||
| Ukucaca kwesixazululo | Kucace kumbala obala kancane.(0.25g/10ml 0.1N Hydrochloric acid) | Kuyavumelana | |
| Ukulahlekelwa ekomisweni | ≤1.0% (Yomisa ku-vacuum ku-120°C) | 0.29% | |
| Izinsalela ekushiseni | ≤0.1% | 0.02% | |
| Izinsimbi ezinzima | ≤20ppm | <20ppm | |
| Ubumsulwa beChromatographic | I-analogue ye-Ciprofloxacin ethylenedianiine | ≤0.2% | 0.07% |
| I-Fluoroquinolonicacid | ≤0.2% | 0.02% | |
| Noma yikuphi okunye ukungcola okukodwa | ≤0.2% | 0.06% | |
| Ukungcola okuphelele | ≤0.5% | 0.19% | |
| (HPLC) Ukuhlolwa | C17H18FN3O3 98.0%~ 102.0% (Ngokomisiwe) | 100.7% | |
| Isiphetho: Ihambisana nokucaciswa kwe-USP41 kwe-Ciprofloxacin | |||
