I-Cimetidine(51481-61-9)
Incazelo Yomkhiqizo
● I-Cimetidine inemiphumela yokuvimbela neyokuvikela ku-gastritis ebolayo ebangelwa ukucasuka kwamakhemikhali, futhi inamandla amakhulu ekucindezelekeni kwesilonda sesisu nokopha kwamathumbu aphezulu.
● I-Cimetidine iyisivimbeli se-histamine H2 receptor, ikakhulukazi esetshenziselwa ukuvimbela ukukhishwa kwe-asidi esiswini, engavimbela ngokuphawulekayo ukukhishwa kwe-basal ne-nocturnal gastric acid, futhi iphinde ivimbele ukukhishwa kwe-asidi esiswini okubangelwa i-histamine, i-fractional peptide gastrin, i-insulin kanye nokuvuselela ukudla, futhi ikwenze i-acidic kancane.I-Cimetidine inomphumela wokuvimbela nokuvikela ku-gastritis ebolayo ebangelwa ukugqugquzelwa kwamakhemikhali, futhi iyasebenza kakhulu ekucindezelekeni kwesilonda sesisu kanye nokopha kwesisu esingenhla.
●Izinga Lekhwalithi: USP
| Into | Okujwayelekile | Umphumela |
| Bhekana | Imhlophe noma icishe ibe i-Crystalline Powder engenaphunga, enambithekayo ebabayo | Confbnn |
| Ukuhlonza | ||
| A:(IR) | Ihambisana ne-USP Cimetidine RS | Vumelanisa |
| B:(UV) | Ihambisana ne-USP Cimetidine RS | Vumelanisa |
| I-Assay (ibalwa ngokwesisekelo esomisiwe) | 98.0-102.0% | 99.9% |
| Ukungcola | ||
| Izinsalela ekushiseni | I-NMT 0.2% | Vumelanisa |
| Izinsimbi ezinzima | I-NMT 20ppm | Vumelanisa |
| Ukungcola okuphilayo | Noma yikuphi ukungcola komuntu ngamunye kwe-NMT 0.2% | I-NMT 0.2% |
| Ukungcola okuphelele kwe-NMT 1.0% | I-NMT 1.0% | |
| Ibanga lokuncibilika noma Izinga Lokushisa | 139-144 °C | 141-143*C |
| Ukulahlekelwa ekomisweni | I-NMT 1.0% | 0.22% |
| Izinyibilikisi ezisele (ethanol) | I-NMT 0.5% | I-NMT 0.5% |
