I-Doxycycline Hyclate(24390-14-5)
Incazelo Yomkhiqizo
● I-Doxycycline Hcl i-antibacterial spectrum isondelene kakhulu ne-Tetracycline ne-Terramycin, kodwa inomphumela ongcono, zwela ku-Staphylococcus Aureus ye-tetracycline-resistant, oxytetracycline, isikhathi eside. ukutheleleka kwamaphaphu, i-acute tonsillitis, inyumoniya ye-mycoplasma, ukutheleleka komgudu womchamo, ubuthi egazini, isifo sohudo, i-acute lymphadenitis, njll. Kudume kakhulu esigulini se-Nephropathy ngenxa yobuthi bayo obungabonakali ezinso.
● I-Doxycycline Hyclate iwuhlobo lukasawoti lwe-hyclate lwe-doxycycline, isibulala-magciwane sokwenziwa, esibanzi se-tetracycline esibonisa umsebenzi wokulwa namagciwane.I-Doxycycline hyclate ibophezela ngokubuyela emuva ku-30S ribosomal subunit, mhlawumbe ne-50S ribosomal subunit futhi, ngaleyo ndlela ivimbe ukubophezela kwe-aminoacyl-tRNA kunxaki ye-mRNA-ribosome.Lokhu kuholela ekuvinjweni kwe-protein synthesis.Ngaphezu kwalokho, le ejenti ibonise ukuvinjelwa komsebenzi we-collagenase.
Isicelo
I-Doxycycline Hyclate isetshenziselwa ukwelapha izifo ezihlukahlukene ezibangelwa amagciwane, kuhlanganise nalezo ezibangela izinduna.I-Doxycycline Hyclate nayo isetshenziselwa ukuvimbela umalaleveva.I-Doxycycline Hyclate yaziwa ngokuthi i-tetracycline antibiotic.Isebenza ngokumisa ukukhula kwamagciwane.Le antibiotic yelapha izifo ezibangelwa amagciwane kuphela.
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | I-crystalline powder ephuzi | Kuyavumelana |
| Ukuhlonza | I-TLC | Kuyavumelana |
| ukusabela kwe-sulfuric acid umbala ophuzi uyakhula | Kuyavumelana | |
| inikeza ukusabela kwe-chloride | Kuyavumelana | |
| PH | 2.0~3.0 | 2.3 |
| Ukumunca okukhethekile | ku-349nm e(1%) 300~355 | 320 |
| Ukujikeleza kwe-optical okuqondile | -105 ~ -120° | -110 ° |
| Izinsimbi ezinzima: | ≤50ppm | <20ppm |
| Ukungcola okumunca ukukhanya | ku-490nm ≤0.07 | 0.03 |
| Izinto ezihlobene | 6-epidoxycycline ≤2.0%metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) i-oxytetracycline ≤0.5% (ep5) noma yikuphi okunye ukungcola ≤0.5% ukungcola okungahlonziwe ≤0.1% (ep5) | 1.6%0.1% Akutholakalanga Akutholakalanga Akutholakalanga Akutholakalanga Akutholakalanga |
| I-Ethanol | 4.3~6.0% (m/m) | 4.5% |
| Umlotha one-sulphate | ≤0.4% | 0.05% |
| Amanzi | 1.4~2.8% | 1.8% |
| Isivivinyo | 95.0 ~ 102.0% ( c22h25cln2o8) okusekelwe entweni engenamanzi, engenayo i-ethanol | 98.6% |
| Isiphetho | Vumelanisa ne-USP32 | |
