I-Thiamine Hydrochloride/ I-Vitamin B1 HCL(67-03-8)
Incazelo Yomkhiqizo
I-Thiamine, eyaziwa nangokuthi i-thiamin kanye ne-vitamin B1, iyivithamini, isakhi esibalulekile esingenakwenziwa emzimbeni.Itholakala ekudleni futhi ihlanganiswe ngokwentengiso ukuze ibe isithasiselo sokudla noma imithi.Izinhlobo ze-phosphorylated ze-thiamine ziyadingeka ekuphenduleni okuthile kwe-metabolic, okuhlanganisa ukuwohloka kwe-glucose nama-amino acid.
Imithombo yokudla ye-thiamine ihlanganisa okusanhlamvu, okusanhlamvu okusanhlamvu, nenye inyama nenhlanzi.Ukugaya okusanhlamvu kususa amavithamini amaningi, ngakho emazweni amaningi okusanhlamvu nofulawa kunothiswa nge-thiamine.[1]Izithasiselo nemithi ziyatholakala ukwelapha nokuvimbela ukushoda kwe-thiamine kanye neziyaluyalu ezivela kukho zihlanganisa i-beriberi ne-Wernicke encephalopathy.Zibuye zisetshenziselwe ukwelapha isifo somchamo isiraphu ye-maple kanye ne-Leigh syndrome.Izithasiselo nemithi ivamise ukuthathwa ngomlomo, kodwa futhi inganikezwa ngomjovo ofakwa emthanjeni noma nge-intramuscular.
I-Thiamine Hydrochloride (I-Vitamin B1 HCL) iyimpushana eyikristalu Emhlophe, inephunga elincane elikhethekile.Incibilika kancane emanzini, incibilika kancane ku-ethanol ne-chloroform, futhi ayincibiliki ku-aether..Isetshenziswa njengezithasiselo zokudla, okuphakelayo kanye nemithi.
Umsebenzi
● Ukuze kuthuthukiswe ukukhula, kusiza ukugaya, ikakhulukazi ekugayweni kwama-carbohydrate.
● Ukuze uthuthukise impilo yengqondo, ugcine izicubu zezinzwa, imisipha, umsebenzi wenhliziyo ovamile.
● Ukuqeda ukugula kokunyakaza, kungadambisa ubuhlungu obuhlobene nokuhlinzwa kwamazinyo.
● Faka isandla ebhendini Njengokwelashwa kwe-herpes (herpes zoster).
| Into yokuhlola | Ukucaciswa | Umphumela | |
| BP2013 | ukubukeka | emhlophe noma ecishe ibe mhlophe, i-crystalline powder noma amakristalu angenambala | i-crystalline powder emhlophe |
| PH | 2.7~3.3 | 3.0 | |
| Amanzi | ≤5.0% | 3.38% | |
| umlotha we-sulphated | ≤0.1% | 0.02% | |
| ama-sulphate | ≤300ppm | <300ppm | |
| izinsimbi ezinzima | ≤20ppm | <20ppm | |
| I-Assay (ngokwesisekelo se-anhydrous) | 98.5%~101.0% | 99.5% | |
| I-USP36 | ukuhlonza | A:Ukumuncwa kwe-IR;B:ukuhlolwa kwe-chloride. | thobela |
| ukumuncwa kwesixazululo | ≤0.025 | 0.016 | |
| umkhawulo we-nitrate | ayikho indandatho ensundu ekhiqizwa lapho kuhlangana lezi zingqimba ezimbili | thobela | |
| ph | 2.7~3.4 | 3.2 | |
| amanzi | ≤5.0% | 3.38% | |
| ≤0.2% | 0.02% | ||
| ≤1.0% | 0.06% | ||
| I-Assay (ngokwesisekelo se-anhydrous) | 98.0%~102.0% | 99.7% |
