I-Tilmicosin Phosphate(137330-13-3)
Incazelo Yomkhiqizo
● I-Tilmicosin phosphate iyi-chemical semi-synthetic macrolide antibiotic.Isidakamizwa esisha esiqondene nesilwane esinomuthi obanzi wokulwa namagciwane.I-Tilmicosin phosphate inamandla ngokumelene nama-bacteria e-gram-negative kanye ne-positive.Ibuye ibe nomphumela oqinile wokuvimbela ezinhlobonhlobo ze-mycoplasma nama-spirochetes.
● I-Tilmicosin phosphate ngokuvamile isetshenziselwa izifo zokuphefumula ezibangelwa i-Actinomyces pleuropneumoniae, i-Pasteurella hemolyticus, i-Pasteurella multocida, nemizimba yemfuyo nezinkukhu.
| Izinto | Imininingwane | Imiphumela |
| Izinhlamvu | Impushana emhlophe noma ecishe ibe mhlophe | Cishe impushana emhlophe |
| Ukuhlonza | Ukuhlolwa kwe-IR:Ihambisana nereferensi | Kuyavumelana |
| Ukuhlolwa kwe-HPLC: Ihambisana nereferensi | Kuyavumelana | |
| Isampula elizohlolwa libonisa ukusabela kwe-phosphate. | Kuyavumelana | |
| Amanzi | ≤7.0% | 3.0% |
| pH | - | 6.7 |
| Izinhlanganisela ezihlobene | Noma iyiphi inhlanganisela ehlobene nomuntu ≤3% | 3% |
| Isamba sazo zonke izinhlanganisela ezihlobene≤10% | 5% | |
| I-Assay (isisekelo esomisiwe) | I-Timicosin iqukethe i-C46H80N2O13≥75% | 79.2% |
| Okuqukethwe kwe-tilmicosin cis-isomers kuphakathi kuka-82. 0% no-88. 0% | 85. 0% | |
| okuqukethwe kwe-tilmicosin trans-isomers kuphakathi kuka-12. 0% no-18. 0% | 15.0% |
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